Product Introduction
Bioactivity


英文名: NAE-IN-M22

描述: NAE-IN-M22 (NEDD8 inhibitor M22) 是一种选择性可逆的 NEDD8 激活酶抑制剂。 它抑制多种癌细胞系并诱导 A549 细胞凋亡，还可以在体内抑制肿瘤生长。

体外活性: NAE-IN-M22作为一种选择性NAE抑制剂。M22对NAE具有可逆性，能在低微摩尔范围内抑制多种癌细胞系的生长，GI50值低，并在A549细胞中诱导凋亡。

体内活性: NAE-IN-M22是一种选择性NAE抑制剂。M22对NAE具有可逆性，能在低微摩尔范围内抑制多种癌细胞系的生长(GI50值)，并在A549细胞中诱导凋亡。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 250 mg/mL (688.10 mM)


关键字: NAEINM22 | cancer | Inhibitor | NAE-IN-M-22 | NAE | NEDD8 | NAE IN M22 | enzyme | activating | inhibit | tumor | NAE-IN-M22 | Apoptosis

相关产品: Dehydrotrametenolic acid | Coniferaldehyde | Gomisin N | Pinoresinol | saponaretin | Baohuoside I | BMS-833923 | L-Glutamic acid monosodium salt | SCR7 pyrazine | Tandutinib

相关库: HIF-1 Signaling Pathway Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Ubiquitination Compound Library | Inhibitor Library | Anti-Cancer Active Compound Library | Apoptosis Compound Library | NO PAINS Compound Library | Bioactive Compound Library