Product Introduction
Bioactivity


英文名: TIE-2/VEGFR-2 kinase-IN-1

描述: TIE-2/VEGFR-2 kinase-IN-1 用于合成TIE-2或者VEGFR-2抑制剂，可用于研究不适当的血管生成的相关疾病。

体外活性: Angiopoieten 1 is a ligand for the endotheiium-specific receptor tyrosine kinase, TIE-2 is a novel angiogenic factor [1].Inhibition of TIE-2 is expected to serve to disrupt remodeling and maturation of new vasculature initiated by angiogenesis, thus disrupting the angiogenic process. Inhibition at the kinase domain binding site of VEGFR-2 would block phosphorylation of tyrosine residues and serve to disrupt initiation of angiogenesis.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: TIE-2/VEGFR-2 kinase-IN-1 | TIE 2/VEGFR 2 kinase IN 1 | TIE2/VEGFR2 kinaseIN1