产品名称：胆固醇氧化酶 来源于微生物

规格或纯度：EnzymoPure™, ＞10U/mg

生化机理：胆固醇氧化酶及胆固醇脂酶一起用于血脂类项目如高密度脂蛋白（HDL-C）、低密度脂蛋白（LDL-C）以及总胆固醇（CHO）等。

产品介绍：

Cholesterol oxidase has been used in a study to improve treatment of oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used in a study that determined that cholesterol depletion impairs coupling between channel opening and vesicle release by allowing voltage-gated calcium channels to move further from release sites. Cholesterol oxidase has been used in a study to improve treatment of oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used in a study that evaluated the effects of cholesterol depletion. This study reported that cholesterol depletion impairs the coupling between channel opening and vesicle release. Additionally, cholesterol oxidase is used to determine serum cholesterol levels. The enzyme also finds application in the microanalysis of steroids in food samples. It has also been used for distinguishing 3-ketosteroids from 3β-hydroxysteroids. Transgenic plants expressing cholesterol oxidase have been investigated in the fight against the cotton boll weevil. CHOD has also been used as a molecular probe to elucidate cellular membrane structures.来自链霉菌的胆固醇氧化酶已用于评估模拟胆汁的胶束结构与酯酶活性之间的关系。来自链霉菌的胆固醇氧化酶还被用于研究鞘磷脂降解对细胞胆固醇氧化性以及细胞表面与细胞内部之间稳态分布的影响。 胆固醇氧化酶可用于检测血清胆固醇。该酶还可用于对食品样品中的类固醇进行微量分析以及用于区分3-酮类固醇与3β-羟基类固醇。目前正在研究表达胆固醇氧化酶的转基因植物对棉铃象虫甲的抵抗性。CHOD也被作为分子探针，用于阐明细胞膜结构。

级别：EnzymoPure™

浓度：＞10U/mg

储存温度：-20°C储存

运输条件：超低温冰袋运输

CAS编号和信息：9028-76-6

酶学委员会编号：1.1.3.6

单位定义：One unit will convert 1.0 μmole of cholesterol to 4-cholesten-3-one per min at pH 7.5 at 25 °C. Note: 4-cholesten-3-one may undergo isomerization

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