Product Introduction
Bioactivity


英文名: XMD-17-51 Trifluoroacetate

描述: XMD-17-51 Trifluoroacetate 是可调控蛋白激酶的嘧啶-安定酮化合物。

体外活性: XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone compound that is able to modulate protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK, ULK2, PLK, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC. XMD-17-51 Trifluoroacetate can be used in the treatment of various diseases, disorders or conditions [1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 8 mg/ml (19.78 mM)
H2O : 2 mg/ml (4.94 mM)
DMSO : 80 mg/ml (197.78 mM)


关键字: 1628614-50-5 | 1628614-50-5 free base | XMD 17 51 Trifluoroacetate | XMD1751 Trifluoroacetate | XMD-17-51 Trifluoroacetate

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