Product Introduction
Bioactivity


英文名: Sisunatovir hydrochloride

描述: Sisunatovir hydrochloride (RV521 HCl) 是一种可口服的 RSV-F 蛋白抑制剂，在体外对一组 RSV-A 和 RSV-B 病毒的临床分离株表现出有效的疗效，对 RSV-A 和 RSV-B 分离株的IC50分别为 1.4 nM 和 1.0 nM。

体外活性: Sisunatovir HCl exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 5.5 mg/ml (11.39 mM)


关键字: antiviral | RV521 | Inhibitor | Sisunatovir Hydrochloride | Sisunatovir hydrochloride | syncytial | RV 521 | Respiratory syncytial virus | respiratory | viral | RV-521 | inhibit | RSV | Sisunatovir

相关产品: Ac-CoA Synthase Inhibitor1 | VV116 | RSV604 | RSV L-protein-IN-4 | 4-Methoxycinnamaldehyde | RSV L-protein-IN-2 | RSV L-protein-IN-3 | JNJ-8003 | Amentoflavone | Roflumilast

相关库: Drug Repurposing Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Orally Active Compound Library | NO PAINS Compound Library | Anti-Viral Compound Library | Bioactive Compound Library | Anti-Infection Compound Library