Product Introduction
Bioactivity


英文名: Cimicifugoside H-1

描述: Cimicifugoside H1 是C. foetidaL.C 提取物的主要成分，是一种环甾烷醇木糖苷。它对骨吸收及卵巢切除术引起的骨质流失具有抑制作用。

体外活性: The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition activity was then studied.Thirteen cycloartane triterpenoids were isolated from the rhizomes of C. foetida and were characterized as 25-O-acetyl-cimigenol (1), cimigenol (2), cimicidanol (3), 26-deoxyactein (4), asiaticoside A (5), 23-epi-26-deoxyactein (6), actein (7), 12beta-hydroxycimigenol (8), cimiside E (9), (23R, 24S) 25-O-acetyl-cimigenol-3-O-beta-D-xylopyranoside (10), (23R, 24S) cimigenol-3-O-beta-D-xylopyranoside (11), Cimicifugoside H1 (12) and Cimicifugoside H2 (13).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 6.17 mg/mL (10 mM)


关键字: bone | Inhibitor | Cimicifugoside H-1 | xyloside | resorption | Cimicifugoside H1 | C. foetida | ovariectomy | cyclolanostanol | loss | inhibit | Cimicifugoside H 1

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