Product IntroductionBioactivity英文名:
Tessaric acid描述: Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
体外活性: METHODS AND RESULTS:A series of analogs were synthesized in a straightforward manner from naturally available sesquiterpenes ilicic acid and Tessaric acid. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, HBL-100, HeLa, SW1573, T-47D and WiDr. The most potent analog induced considerably growth inhibition in the range 1.9-4.5 microM. CONCLUSIONS: Cell cycle studies for Tessaric acid derivatives indicated a prominent arrest of the cell cycle at the G(2)/M phase. Damage to the cells was permanent as determine by the so called 24+24 drug schedule.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Tessaric acid