中文名:NG-单甲基-L-精氨酸乙酸盐
英文名:NG-Monomethyl-L-arginine Acetate
中文别名:NG-甲基-L-精氨酸 乙酸盐|Nω-甲基-L-精氨酸 乙酸盐|NG-一甲基-L-精氨酸 乙酸盐|N5-(甲基脒基)-L-鸟氨酸 乙酸盐|L-NMMA 一乙酸酯|N5-[亚氨基(甲基氨基)甲基]-L-鸟氨酸单乙酸盐
英文别名:L-NMMA acetate|Tilarginine Acetate|53308-83-1|L-NMMA|NG-Monomethyl-L-arginine acetate|NG-Methyl-L-arginine acetate salt|Targinine acetate|Tilarginine acetate [USAN]|L-NMMA (acetate)|ANO-1020|Ng-methylarginine acetate|N-Omega-monomethyl-L-arginine acetate|
纯度:10mM in Water
货号:N424563
Cas号:53308-83-1
存储温度:-80℃储存
产品介绍:
L-NG-Monomethylarginine, Acetate Salt (L-NMMA), is an analogue of L-arginine that has been shown to inhibit Ca2+-dependent NOS3 (endothelial NOS) from porcine aorta. In an experiment on porcine aortic rings, L-NMMA was shown to cause contraction and inhibition of the endothelium-dependent relaxation induced by acetylcholine. This compound has also been noted to elicit a dose-dependent increase in mean systemic arterial blood pressure accompanied by bradycardia. Experiments on cat vascular endothelia show that L-NMMA can increase leukocyte adherence and emigration and reduce venular shear rate. Low shear rates have been shown to promote platelet-endothelial and leukocyte-endothelial cell adhesion in mesenteric venules. L-NG-Monomethylarginine, Acetate Salt (L-NMMA) is an inhibitor of NOS1 and NOS2.
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