中文名：Q-葡聚糖

英文名：Q-dextran

中文别名：Q -dextran 70;O-Trimethylammonium-glycidyl-dextran

英文别名：Q -dextran 70;O-Trimethylammonium-glycidyl-dextran

纯度：70 kDa

货号：Q292463

存储温度：2-8°C储存,充氩,干燥

产品介绍：

Q-dextran is a polycationic derivative of dextran. These derivatives are distinct from DEAE-dextrans in that they only contain quaternary amine groups. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide range of pH (pH 4-10). Q-dextrans will also have a much stronger net charge than corresponding DEAE-dextrans. All batches are checked for molecular weight, degree of substitution and loss on drying. Aladdin produce Q-dextran from 4 kDa to 150 kDa. Q-dextrans are supplied as a white powder.

Structure

Q-dextrans are synthesised by reacting dextran fractions with 2,3-epoxypropyltrimethylammonium chloride. The nitrogen content is approximately 2% which corresponds to one quaternary ammonium group for every four glucose units.

Application

Polycationic products exhibit a wide variety of effects in cellular systems and are of interest as adjuvants in vaccines. Q-dextran has a much stronger net charge than corresponding DEAE-dextrans and will thus give enhanced responses in systems where this effect is important.

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