产品性能结核分枝杆菌蛋白质：＞4000种，覆盖结核分枝杆菌标准株H37Rv基因组所编码蛋白质的95%以上
一张芯片上的点阵数目：1
点样环境：温度4-8℃，湿度30%~40%
芯片基片：晶芯高分子三维基片，尺寸为75*25 mm
点直径：~120微米
样品重复：每个样品重复两个点；
点间距：X向270微米，Y向300微米（圆心距）
点体积：0.5~1 nl/点
芯片点制后处理：4℃过夜固定后-80℃长期保存
产品应用1. 药物作用靶标发现及药物作用机理研究
2. 血清标识物和新免疫原的发现
3. 病原宿主相互作用研究
4. 蛋白质翻译后修饰研究
5. 非编码RNA作用机制研究
6. 蛋白质与DNA相互作用研究
参考文献1.Deng, Jiaoyu, et al. "Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity." Cell reports 9.6 (2014): 2317-2329.[PubMed]2. Zhang Y, et al. Identification of novel efflux proteins Rv0191, Rv3756c, Rv3008 and Rv1667c involved in pyrazinamide resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2017. [PubMed]
3. Hai-Nan Zhang, et al. Cyclic di-GMP regulates Mycobacterium tuberculosis resistance to ethionamide. Scientific Reports 7, Article number: 5860 (2017). [PubMed]4. Jing Wang, et al. The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection. Scientific Reports 6, Article number: 34827 (2016). [PubMed]
5. Wu FL, et al. The Ser/Thr Protein Kinase Protein-Protein Interaction Map of M. tuberculosis. Mol Cell Proteomics. 2017 Jun 1. [PubMed]
6. He X et al. Systematic Identification of Mycobacterium tuberculosis Effectors Reveals that BfrB Suppresses Innate Immunity, MCP. 2017.[PubMed]
