D137738-100g焦碳酸二乙酯(DEPC)
¥
559.00
- 阿拉丁
- 生产商
- D137738-100g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C6H10O5
- 分子量162.14
- Beilstein号 637031
- EC号 216-542-8
- MDL号 MFCD00009106
- PubChem编号 24849799
属性
沸点 | 93-94°C |
折光率 | 1.396-1.4 |
敏感性 | 对热和湿度敏感 |
溶解性 | Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in water with hydrolytic decomposition yielding ethanol and CO2., Soluble in chloroform, ethanol (50% w/w), esters, ketones, and hydrocarbons.Slowly soluble in wate |
存贮条件 | 储存温度 2-8°C; 充氩保存 |
密度 | 1.1010 |
描述
应用 | 蛋白质组氨酸和酪氨酸的修饰试剂。也是RNA酶的化学修饰剂,它和RNA酶的活性基团组氨酸的咪唑环反应而抑制RNA酶活性。 |
产品介绍 | Diethyl Pyrocarbonate has been shown to inhibit ryanodine binding to ryanodine/Ca2+ receptor channels in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. This compound could be useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Diethyl Pyrocarbonate also inhibits PAF Acetylhydrolase (platelet-activating factor acetyl hydrolase), and has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes. |
生化机理 | 在溶液中浓度约为 0.1% (v/v) 时可使 RNase 失活,从而防止 RNA 被降解。 |
别名 | 氧二甲酸二乙酯;DEPC;DEP;氧二甲酸二乙酯;焦炭酸二乙酯;重碳酸二乙酯;DEP; DEPC; Diethyl dicarbonate; Diethyl oxydiformate; Ethoxyformic acid anhydride; Pyrocarbonic acid diethyl ester; |
标识符号 |
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信号词 | Warning |
危害声明 | H302,H315,H319,H335 |
警示性声明 | P261,P305+P351+P338 |
个人防护设备 | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
RTECS | LQ9350000 |
WGK德国 | 3 |
闪点(摄氏) | 69℃ |
风险声明 (欧洲) | R22;R36/37/38 |
安全声明(欧洲) | S26;S36 |
危害码(欧洲) | Xn |
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