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CAS No. : 1354691-97-6
MCE 国际站:Leniolisib phosphate
产品活性:Leniolisib (CDZ173) phosphate 是高效,选择性的 PI3Kδ 抑制剂。Leniolisib phosphate 有潜力用于免疫缺陷类疾病的研究。
研究领域:PI3K/Akt/mTOR
作用靶点:PI3K
In Vitro: Expression of APDS mutant p110δ in cell lines and patient-derived lymphocytes lead to increased pathway activity, measured as phosphorylation of AKT or S6, which is suppressed by Leniolisib phosphate in a concentration dependent way.
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