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MCE 国际站:IL-3 Protein, Canine
IL-3 Protein, Canine是一种造血生长因子,参与多能造血细胞的存活,增殖和分化。
Synonyms: rCaIL-3; Mast cell growth factor; MCGF; Hematopoietic growth factor
Species: Canine
Source: E. coli
Biological Activity: The ED50 is <0.2 ng/mL as measured by human TF-1 cells, corresponding to a specific activity of >5.0 × 106 units/mg.
研究背景:Interleukin-3 (IL-3) is a multipotent hematopoietic growth factor produced by activated T cells, monocytes/macrophages and stroma cells. Addition of IL-3 to the culture medium induces proliferation, maturation and probably self-renewal of pluripotent hematopoietic stem cells and cells of myeloid, erythroid and megakaryocytic lineages. IL-3 preferentially supports the proliferation and differentiation of progenitors at early stages of hematopoietic development. In addition, IL-3 exerts a wide spectrum of biological activities on various target cell populations, including T cells, B cells, eosinophils, basophils and monocytes.
蛋白编号:Q9BDX4 (R24-P143)
基因 ID:481497
产品分类:细胞因子和生长因子 | 集落刺激因子 | 多能集落刺激因子
Categories:Cytokines and Growth Factors | CSF & Receptors | Multi-CSF/IL-3
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