产品名称：碳酸酐酶 来源于牛红细胞

规格或纯度：EnzymoPure™, ≥3,000 units/mg dry weight

生化机理：碳酸酐酶是一种锌金属酶，分子量约为 30,000 Da。该酶催化二氧化碳水合为碳酸。它参与重要的生理和病理过程，如 pH 值和二氧化碳的平衡、碳酸氢盐和二氧化碳的运输、生物合成反应、骨吸收、钙化和肿瘤生成。因此，这种酶是抑制剂的一个重要靶点，临床应用于各种病症，如青光眼、癫痫和帕金森病。

产品介绍：

Carbonic anyhdrase is useful in carboxy group transfers and reduction reactions.Carbonic anhydrase from bovine erythrocytes (BCA) has been used to study the effect of removal of enzyme-bound metal ion, Zn2+, on aggregation behavior of the enzyme. Removal of metal ion by a chelator such as EDTA enhances the propensity of the enzyme to adopt the molten-globule state. This state of the enzyme is found to bind to the chaperone-like α-crystallin and prevent aggregation. The enzyme from Aladdin has been immobilized to electrochemical transducers in order to obtain develop an analytical device for dissolved CO2 measurement. It has also been used for the thermodynamic analysis of conformational changes in BCA.

级别：EnzymoPure™

浓度：≥3,000 units/mg dry weight

储存温度：2-8°C储存

运输条件：冰袋运输

CAS编号和信息：9001-03-0

酶学委员会编号：4.2.1.1

单位定义： One Unit is determined by the electrometric method of Wilbur and Anderson (J. Biol. Chem., 176, 147 (1948)), in which the time required (in seconds) for a saturated CO2 solution to lower the pH of 0.02M Tris-HCl buffer from 8.3 to 6.3, at 0-4°C is determ

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