| 产品介绍 |
TAE226 (NVP-TAE226)是一种有效的FAK抑制剂，IC50为5.5 nM，最有效作用于Pyk2，对InsR， IGF-1R， ALK和c-Met作用效果比其弱10到100倍左右 |
| 备注 |
NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. |
| 生化机理 |
NVP-TAE 226(TAE226) is a potent dual FAK/IGF-IR kinase inhibitor. |
| 别名 |
2-[[5-氯-2-[[2-甲氧基-4-(4-吗啉基)苯基]氨基]-4-嘧啶基]氨基]-N-甲基苯甲酰胺;2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzamide |
