N129972-25mgNutlin-3a
面议
- 阿拉丁
- 生产商
- N129972-25mg
- 现货
- 全国
规格 |
---|
耗材描述
- 分子式 C30H30Cl2N4O4
- 分子量581.49
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
备注 | Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM. |
生化机理 |
Nutlin-3 is MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Antiproliferative agent;chemotherapeutic agent; induces apoptosis in cancer cells. |
别名 | (-)-Nutlin-3;2-Piperazinone, 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-;(-)-Nutlin-3;2-Piperazinone, 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]- |
猜你喜欢
感兴趣产品