耗材描述
- 分子式 C11H14ClNO3
- 分子量243.69
- Beilstein号
- EC号 MFCD01326592
- MDL号 MFCD01326592
- PubChem编号
属性
| 溶解性 |
|
| 存贮条件 | 储存温度2-8℃ |
描述
| 产品介绍 | Droxinostat |
| 备注 | Droxinostat (CMH, 5809354) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10. |
| 生化机理 |
Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 (IC50 at 16.9 ,2.47 and 1.46 μM, respectively). |
| 别名 | ;4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide |
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