C124969-1gCapecitabine
面议
- 阿拉丁
- 生产商
- C124969-1g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C15H22FN3O6
- 分子量359.35
- Beilstein号
- EC号 MFCD00930626
- MDL号
- PubChem编号
属性
溶解性 | Soluble in water (26 mg/ml), ethanol (207 mg/ml), methanol (> 40%), DMF (~14 mg/ml), and DMSO (72 mg/ml at 25 °C). |
存贮条件 | 储存温度-20°C |
描述
应用 | An antiproliferative 5-fluorouracil releasing compound |
产品介绍 | Capecitabine是一种治疗肿瘤选择性的氟嘧啶氨基甲酸酯,具有较高的瘤内5-FU水平,且毒性比5-FU低。 |
备注 | Capecitabine is a tumor-selective fluoropyrimidine carbamate which achieves higher intratumoral 5-FU level with lower toxicity than 5-FU. |
生化机理 | Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil. From Wikipedia. |
别名 | 卡培他滨;5'-脱氧-5-氟-N4-[(戊氧基)羰基]胞啶;Ro-9-1978;5′-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine;5'-Deoxy-5-fluoro-N4-[((pentyloxy)carbonyl]cytidine |
信号词 | Danger |
危害声明 | H341-H350-H360FD |
警示性声明 | P201-P281-P308 + P313 |
WGK德国 | 3 |
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