S129890-10mgSRT1720
面议
- 阿拉丁
- 生产商
- S129890-10mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C25H23N7OS.HCl
- 分子量506.02
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
应用 | A selective SIRT1 activator |
产品介绍 | SRT1720是一种选择性的SIRT1激活剂,EC50为0.16 μM,比作用于SIRT2和SIRT3效果弱230倍以上。 |
备注 | SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3. |
生化机理 | SRT1720 is an NAD-dependent deacetylase sirtuin-1 (SIRT1) activator (EC50 = 0.16 μM), highly selective for SIRT1 over SIRT2 or SIRT3. Studies in yeast suggest that sirtuins may be involved in epigentic gene silencing and deactylation of proteins that regulate the cell cycle. |
别名 | SRT-1720;SRT 1720; N-[2-[3-(1-哌嗪甲基)咪唑并[2,1-b]噻唑-6-基]苯基]-2-喹喔啉甲酰胺盐酸盐;SRT-1720;SRT 1720;SRT 1720 Hydrochloride;N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide hydrochloride |
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