P126351-50mgPCI-34051
面议
- 阿拉丁
- 生产商
- P126351-50mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C17H16N2O3
- 分子量296.32
属性
溶解性 | 59 mg/mL in DMSO <1 mg/mL in Water 1 mg/mL in Ethanol |
存贮条件 | 储存温度-20°C |
描述
应用 | A potent and specific HDAC8 inhibitor. |
产品介绍 | PCI-34051是一种有效的,特异性的HDAC8抑制剂,无细胞试验中IC50为10 nM。比作用于HDAC1和6选择性高200多倍,比作用于HDAC2, 3,和10选择性高1000倍。 |
备注 | PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. |
生化机理 | PCI-34051 is a potent and specific HDAC8 (histone deacetylase 8) inhibitor (IC50 = 10 nM). PCI-34051 reveals greater than 200-fold selectivity over HDAC1 and HDAC6, and greater than 1000-fold selectivity over HDAC2, HDAC3 and HDAC10. |
别名 | PCI 34051; N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺;PCI 34051;PCI34051;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;N-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide |
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