| 应用 |
A CB1 receptor allosteric modulator. |
| 产品介绍 |
Org 27569是cannabinoid CB1 receptor变构调节剂，通过增强激动剂亲和力而诱导CB1受体状态改变，且降低逆向激动剂的亲和力。 |
| 备注 |
Org 27569 is an allosteric modulator of cannabinoid CB1 receptor, induces a CB1 receptor state that is characterized by enhanced agonist affinity and decreased inverse agonist affinity. |
| 生化机理 |
Org 27569 is a CB1 receptor allosteric modulator. Exhibits increased binding of the CB1 agonist. Inhibits CB1 receptor antagonist effectiveness in vitro. |
| 别名 |
Org-27569; 5-氯-3-乙基N-[2-(4-哌啶-1-基)苯基乙基]-1H-吲哚-2-甲酰胺;5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide;Org-27569 |
