A125440-10mgAnamorelin
面议
- 阿拉丁
- 生产商
- A125440-10mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C31H42N6O3
- 分子量546.70
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
产品介绍 | Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. |
生化机理 |
Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. |
别名 | RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643;阿拉莫林; (3R)-1-(2-甲基丙氨酰-D-色氨酰)-3-苯甲基-3-哌啶 1,2,2-三甲基甲酰肼;RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643;(3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide |
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