B129446-1gAmfebutamone (Bupropion) HCl
面议
- 阿拉丁
- 生产商
- B129446-1g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C13H18ClNO.HCl
- 分子量276.20
- Beilstein号
- EC号
- MDL号 MFCD00055209
- PubChem编号
属性
熔点 | 233-234°C |
溶解性 | Soluble in water (>25 mg/ml), ethanol 193mg/ml, 0.1 N HCl 333 mg/ml |
存贮条件 | 储存温度 2-8°C |
描述
应用 | An inhibitor of dopamine and SLC6A2. |
产品介绍 | Amfebutamone (Bupropion) HCl是一种选择性去甲肾上腺素-多巴胺再摄取的抑制剂,IC50分别为6.5和3.4μM。 |
备注 | Amfebutamone HCl is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrine, respectively |
生化机理 | Bupropion HCl is a non-selective inhibitor of dopamine and SLC6A2 (Ki values are 1.4 μM for SLC6A2, 2.8 μM for dopamine, and 45 μM for serotonin). Bupropion also inhibits neuronal nicotinic acetylcholine receptors. Bupropion HCl is an inhibitor of AChR, DAT and ST. |
别名 | 盐酸安非他酮; 1-(3-氯苯基)-2-[(1,1-甲基乙基)氨基]-1-丙酮盐酸盐;(±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride;Bupropion hydrochloride;Amfebutamone hydrochloride; Wellbutrin; Zyban; Budeprion;2-(tert-Butylamino)-1-(3-chlorophenyl)-1-propanone Hydrochloride |
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