Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Phase 3.
别名
1-[2-[(2,4-二甲基苯基)硫基]苯基]哌嗪氢溴酸盐;Lu AA 21004 hydrobromide; Lu AA21004 hydrobromide;1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide;Vortioxetine hydrobromide