A129982-100g5-氨基水杨酸
面议
- 阿拉丁
- 生产商
- A129982-100g
- 现货
- 全国
规格 |
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耗材描述
- 分子式 H2NC6H3-2-(OH)CO2H
- 分子量153.14
- Beilstein号 2090421
- EC号 201-919-1
- MDL号 MFCD00007877
- PubChem编号 24890780
属性
熔点 | 265°C |
敏感性 | 对光和空气敏感 |
溶解性 | Soluble in 1 M hydrochloric acid (50 mg/ml), water (0.84 g/l at 20 °C), alcohol, DMSO (~4 mg/ml), DMF (~1.6 mg/ml), PBS(pH=7.2) (~1.7 mg/ml), methanol, water (1.7 mg/ml at 25 °C), and ethanol (31 mg/ml at 25 °C). Insoluble in diethyl ether, and n-octan |
存贮条件 | 储存温度 2-8°C ,充氩储存 |
描述
应用 | 5-氨基水杨酸是一种适用于 ELISA 分析的过氧化物酶底物。该底物生成棕色的可溶性终产物,该产物可通过分光光度法在 450nm 处读取。加入 3N NaOH 可终止反应,然后在 550nm 处进行读取。 |
产品介绍 | Mesalamine是一种抗炎化合物。 |
备注 | Mesalamine is an anti-inflammatory compound. |
生化机理 | 5-Aminosalicylic Acid, the metabolite of sulphasalazine, has been shown to inhibit PGDH (prostaglandin 15-hydroxydehydrogenase) in human placenta and bovine lung. Further studies show that this antiinflammatory compound also inhibits leukotriene formation in human leukocytes. Additionally, 5-Aminosalicylic acid demonstrates the ability to disrupt TNFα (tumor necrosis factor α)-stimulated NFκB (nuclear factor κB) activation via inhibition of the multimeric IκB kinase regulating complex. |
别名 | 5-AS;5-氨基-2-羟基苯甲酸;氨水杨酸;美沙拉秦;5-氨基-2-羟基苯甲酸;3-羧基-4-羟基苯胺;5-Amino-2-hydroxybenzoic acid;5-AS;Mesalamine;Mesalazine;5-Amino-2-hydroxybenzoic Acid |
Reaxys-RN | 2090421 |
标识符号 |
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信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | VO1400000 |
WGK德国 | 2 |
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