E126824-250mgEltrombopag
面议
- 阿拉丁
- 生产商
- E126824-250mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C25H22N4O4
- 分子量442.47
属性
溶解性 | 25°C: DMSO 89 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
描述
应用 | An agonist of the thrombopoietin receptor |
产品介绍 | Eltrombopag 是小分子,c-mpl (TpoR) 受体激动剂,抑制 hERG K+通道尾电流,IC50为0.69 μM。 |
备注 | Eltrombopag is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current. |
生化机理 | An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia. |
别名 | SB-497115-GR, Revolade, Promacta;伊屈泼帕; 3'-[2-[(2Z)-1-(3,4-二甲基苯基)-1,5-二氢-3-甲基-5-氧代-4H-吡唑-4-亚基]肼基]-2'-羟基-[1,1'-联苯]-3-羧酸;SB-497115;SB-497115-GR;SB497115;SB 497115;Promacta;3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid |
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