T129425-100mgTirofiban
面议
- 阿拉丁
- 生产商
- T129425-100mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C22H36N2O5S
- 分子量440.6
- Beilstein号 6182267
- MDL号 MFCD05237246
属性
溶解性 |
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存贮条件 | 储存温度-20°C |
描述
产品介绍 | Tirofiban是非肽类,糖蛋白IIb/IIIa拮抗剂。 |
生化机理 | Tirofiban (MK-383, Aggrastat) is a nonpeptide derivative of tyrosine that selectively inhibits the GP-IIb/IIIa receptor, with minimal effects on the ɑvβ3 vitronectin receptor. It inhibits platelet aggregation of gel-filtered platelets induced by 10 μM ADP with IC50 of 9 nM, but the IC50 for inhibition of human umbilical vein adhesion to vitronectin, which depends on ɑvβ3 vitronectin receptors, is 62 μmol/L. |
别名 | 替罗非班; (2S)-2-(丁基磺酰氨基)-3-[4-[4-(4-哌啶基)丁氧基]苯基]丙酸;L700462; MK383;N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl-d6]-L-tyrosine; (2S)-2-(Butylsulfonylamino)-3-[4-[4-(4-piperidyl)butoxy]phenyl]propanoic acid |
标识符号 |
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信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | YP2364100 |
WGK德国 | 3 |
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