S129238-500mgSuplatast Tosylate
面议
- 阿拉丁
- 生产商
- S129238-500mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C23H33NO7S2
- 分子量499.64
- MDL号 MFCD00867604
属性
溶解性 | Soluble in water (100 mg/ml at 25 °C), DMSO (100 mg/ml at 25 °C), ethanol (100 mg/ml at 25 °C), and methanol (very). |
描述
应用 | Th2细胞因子抑制剂,甲磺司特可以用于研究免疫信号。 |
产品介绍 | Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Shows antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active. |
备注 | Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM. |
生化机理 |
Suplatast Tosilate(IPD 1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Suplatast Tosilate(IPD 1151T) exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active. |
别名 | 2-[4-(3-乙氧基-2-羟基丙氧基)苯氨基甲酰]乙基二甲基硫对甲苯磺酸盐;甲磺司特;IPD-1151T;ST;(+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate;2-[4-(3-Ethoxy-2-hydroxypropoxy)phenylcarbamoyl]ethyldimethylsulfonium p-Toluenesulfonate |
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