A128036-25mgAZD5363
面议
- 阿拉丁
- 生产商
- A128036-25mg
- 现货
- 全国
规格 |
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耗材描述
属性
溶解性 |
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存贮条件 | 储存温度-20°C |
描述
产品介绍 | AZD5363是各种AKT亚型抑制剂,IC50<10nM。 |
生化机理 | AZD5363, a novel pyrrolopyrimidine-derived compound, inhibited all AKT isoforms with a potency of 10 nmol/L or less and inhibited phosphorylation of AKT substrates in cells with a potency of approximately 0.3 to 0.8 μmol/L. AZD5363 monotherapy inhibited the proliferation of 41 of 182 solid and hematologic tumor cell lines with a potency of 3 μmol/L or less。 |
别名 | AZD-5363;AZD 5363;4-氨基-N-((1S)-1-(4-氯苯基)-3-羟基丙基)-1-(7H-吡咯并(2,3-d)嘧啶-4-基)-4-哌啶甲酰胺;;AZD-5363;AZD 5363; 4-amino-n-((1s)-1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-4-piperidinecarboxamide |
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