A126209-5mgAT7867
面议
- 阿拉丁
- 生产商
- A126209-5mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C20H20ClN3
- 分子量337.86
属性
沸点 | 530.2 °C/760 mmHg |
溶解性 | DMSO ≥66mg/mL Water <1.2mg/mL Ethanol ≥4.6mg/mL |
存贮条件 | 储存温度-20°C |
密度 | 1.2000 |
描述
应用 | A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3 |
产品介绍 | AT7867是ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂,IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM,对AGC激酶家族以外的蛋白几乎无活性。 |
备注 | AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. |
生化机理 |
AT7867 is a potent and oral AKT and p70 S6 kinase inhibitor with an IC50 of 17 nM. |
别名 | 4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶;pyrazole-based inhibitor 9;4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine |
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