A131295-1mg7-氨基放线菌素D(7-AAD)
面议
- 阿拉丁
- 生产商
- A131295-1mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C62H87N13O16
- 分子量1270.43000
- Beilstein号
- EC号
- MDL号 MFCD00077295
- PubChem编号
属性
熔点 | 252-253 °C |
敏感性 | 对光和湿度敏感 |
溶解性 | Soluble in DMSO (20 mg/ml), ethanol, chloroform (1 mg/ml), and dichloromethane (20 mg/ml). |
存贮条件 | 储存温度-20℃ |
描述
应用 | A fluorescent DNA dye for apoptosis and flow cytomtery studies. |
产品介绍 | 7-Aminoactinomycin D ,an analog of the antibiotic actinomycin D ,is a fluorescent DNA dye which is useful for quantifying apoptosis. 7-AAD has also been used in studies on cellular necrosis, chromosome analysis and in cell cycle studies. As a fluorescent DNA dye, 7-AAD is able to intercalate DNA via binding to the GC regions. When used in flow cytometery, 7-AAD can be used to discriminate between live cells as well as early and late apoptosis. Additionally, 7-AAD can also be combined with other staining procedures for analysis of intracellular and cell surface antigens enabling multiparametric analysis. When utilizing 7-AAD with flow cytometery, early and late apoptosis can be studied by varying the concentration of 7-AAD. During apoptosis, the cellular plasma membrane is altered progressively, which allows the cell membrane to become permeable to 7-AAD. 7-AAD staining can also be adapted to include staining with other dyes for intracellular and cell surface antigens. 7-Aminoactinomycin D is an inhibitor of DNA Polymerase and RNA Polymerase |
别名 | 7-AAD; 7-AminoActinomycin D;7-AAD |
信号词 | Danger |
危害声明 | H300 |
警示性声明 | Missing Phrase - N15.00950417 |
个人防护设备 | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
RTECS | AU1579000 |
WGK德国 | 3 |
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