耗材描述
- 分子式 C10H12FN5O4
- 分子量285.23
- Beilstein号 1225932
- EC号 244-525-5
- MDL号 MFCD00132942
- PubChem编号 24894830
属性
| 溶解性 | Soluble in water (<1 mg/mL at 25 °C), DMSO (57 mg/mL at 25 °C), and ethanol (<1 mg/mL at 25 °C). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription |
| 产品介绍 | Fludarabine is a prodrug converted to free nucleoside 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5’-triphosphate. Interferes with DNA synthesis and repair. Induces apoptosis of cancer cells and RNA transcription inhibitor. |
| 别名 | 9-β-D-阿拉伯呋喃糖-2-氟腺苷;2-氟-9-beta-D-arabinofuranosyladenine,;2-F-araA;9-β-D-Arabinofuranosyl-2-fluoroadenine;F-ara-A Fludarabine des-phosphate;2-Fluoroadenine-9-β-D-arabinofuranoside; |
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