G120180-250mg盐酸吉西他滨
面议
- 阿拉丁
- 生产商
- G120180-250mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C9H11F2N3O4·HCl
- 分子量299.66
- Beilstein号
- EC号
- MDL号 MFCD01735988
- PubChem编号
属性
熔点 | 292°C |
折光率 | 268 |
旋光率 | 48°C |
敏感性 | 对热、光线敏感 |
存贮条件 | 储存温度2-8℃ |
描述
生化机理 |
Gemcitabine hydrochloride is used for treatment of non-small cell lung cancer, pancreatic cancer, mammary cancer, ovarian cancer, bladder cancer, nasopharyngeal carcinoma and non-Hodgkin's lymphoma.Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. It displays antitumor activity in vitro and in vivo. |
别名 | dFdC;2'-脱氧-2',2'-二氟胞苷 ;2′-Deoxy-2′,2′-difluorocytidine dFdC dFdCyd |
Reaxys-RN | 5386970 |
标识符号 | GHS08 |
信号词 | Danger |
危害声明 | H360 |
警示性声明 | P201,P308+P313 |
RTECS | HA3840000 |
WGK德国 | 3 |
风险声明 (欧洲) | R63;R62 |
安全声明(欧洲) | S53;S36/37 |
危害码(欧洲) | Xn |
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