耗材描述
- 分子式 C17H19N2OCl
- 分子量302.81
- Beilstein号
- EC号
- MDL号 MFCD00011725
- PubChem编号
属性
熔点 | 250-260°C |
敏感性 | 对光线敏感 |
溶解性 | Soluble in water (30 mg/mL), methyl cellosolve (9 mg/mL), and ethanol (3 mg/mL).DMSO : 25 mg/mL (82.56 mM; Need ultrasonic) |
存贮条件 | 储存温度-20°C |
描述
应用 | Used in Unna-Pappenheim stain to demonstrate RNA (red) in contrast to DNA (green). Also used for bacteria staining. |
产品介绍 | Pyronin Y is a dye that intercalates and stains RNA red, and has been shown to accumulate in the mitochondria of viable cells. Multidrug-resistant (MDR) Acinetobacter baumannii studies tested inhibition of the efflux pump by measuring the intracellluar accumulation of Pyronin Y and Ethidium bromide. Research shows that at low Pyronin Y concentrations the cytostatic effect is cell arrest in the G1 phase, whereas at high concentrations the cells arrest is in the G2 and S phase. Pyronin Y has been used in combination with Alcian Blue to asses and study pulmonary diseases, and in combination with Methyl Green to stain nucleic acids in paraffin sections. Additionally Pyronin Y has been used to measure RNA in flow cytometry. |
别名 | 3,6-双(二甲基氨基)呫吨鎓氯化物,派洛宁Y, 派若宁 G, 派若宁 J;Pyronin G;Pyronin J;3,6-Bis(dimethylamino)xanthylium chloride |
WGK德国 | 3 |
安全声明(欧洲) | S22;S24/25; |
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