N159712-250mg4-(N-马来酰亚胺甲基)环己烷羧酸 -N-琥珀酰亚胺酯
面议
- 阿拉丁
- 生产商
- N159712-250mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C16H18N2O6
- 分子量334.33
- Beilstein号
- EC号
- MDL号 MFCD00009634
- PubChem编号
属性
敏感性 | 对热敏感 ;对光线敏感 ;对湿度敏感 |
存贮条件 | 充氩保存 ;储存温度-20°C |
描述
应用 | A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Contains 9 atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers. |
产品介绍 | 4-(N-马来酰亚胺基甲基)环己烷羧酸 N-羟基琥珀酰亚胺酯(SMCC)是一种异双功能交联剂,其包含一个具有胺和巯基反应性的延长间隔基。[1]它通常首先通过酰胺键(pH7.5(6.5-8.5)缓冲)与含有伯胺的分子进行偶联。第二次偶联通过硫醚键(pH6.8(6.5-7.0)缓冲)与含有游离巯基的分子进行特异性偶联。SMCC包含九个原子连接子。与芳族间隔基相比,延伸的脂族间隔基可在偶联之前稳定马来酰亚胺。 |
别名 | N-琥珀酰亚胺基4-(马来酰亚胺基甲基)环己烷羧酸酯;4-(N-Maleimidomethyl)cyclohexanecarboxylic Acid N-Succinimidyl Ester; SMCC |
Reaxys-RN | 1555271 |
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