Lapatinib,Di-p-ToluenesulfonateSalt,>98%,其它生化试剂

M.Wt: 925.46

Formula: C₂₉H₂₆CIFN₄O₄S · 2C₇H₈O₃S

Solubility: Soluble in DMSO

Purity: >98 %

Storage: Desiccate at -20℃

CAS No: [388082-78-8]

Cat No	Size	Price($)

BC048-100	100mg	135

BC048-500	500mg	325

Biological Activity:

Lapatinib inhibits both epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) tyrosine kinases by binding to the intracellular phosphorylation domain, preventing receptor autophosphorylation. The exact site of binding has currently not been confirmed. It appears to arrest the development of breast cancer in some patients with metastatic, treatment- refractory disease.

Synonym

Tykerb, GW-572016, Tyverb

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