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药物分子
Sildenafil Citrate
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| S129663-25mg | 171599-83-0 | 询价 |
| S129663-1g | 171599-83-0 | 询价 |
| S129663-100mg | 171599-83-0 | 询价 |
| S129663-500mg | 171599-83-0 | 询价 |
产品介绍
- 分子式 C22H30N6O4S·C6H8O7
- 分子量666.70
- MDL号 MFCD09026931
属性
| 熔点 | 185-187 °C |
| 溶解性 | Soluble in water (3.5 mg/ml), DMSO (23 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), methanol, and DMF (~14 mg/ml). |
描述
| 应用 | An orally active selective type 5 cGMP phosphodiesterase inhibitor. |
| 产品介绍 | Sildenafil Citrate是一种治疗勃起功能障碍和肺动脉高压（PAH）的药剂。 |
| 合法信息 | Sold for only research purposes |
| 备注 | Sildenafil citrate is an agent used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). |
| 生化机理 | Sildenafil, Citrate is a citrate form of Sildenafil. Sildenafil is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism. In vitro, increases NO2-dependent relaxation of human corpus cavernosum. |
| 别名 | 枸橼酸西地那非; 1-[4-乙氧基-3-[5-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑并[4,3-d]嘧啶)]苯磺酰]-4-甲基哌嗪枸橼酸盐;1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate salt; 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[5,4-e]pyrimidin-7-one citrate salt; Revatio citrate; UK-92480 citrate; Viagra citrate |
Sildenafil Citrate信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Sildenafil Citrate报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途