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Terbinafine HCl
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| T129278-500g | 78628-80-5 | 询价 |
| T129278-100g | 78628-80-5 | 询价 |
| T129278-1g | 78628-80-5 | 询价 |
| T129278-25g | 78628-80-5 | 询价 |
| T129278-5g | 78628-80-5 | 询价 |
产品介绍
- 分子式 C21H25N·HCl
- 分子量327.89
- MDL号 MFCD00145430
属性
| 沸点 | 417.9° C at 760 mmHg |
| 熔点 | 214℃ |
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch. It is used in adsorption, partition and stability studies. |
| 产品介绍 | Terbinafine盐酸盐是抗真菌化合物，可杀灭皮肤癣菌和双相型真菌，抑制白色念珠菌。 |
| 生化机理 | Terbinafine hydrochloride is a synthetic allylamine antifungal, which is highly active against dermatophytes, mold, other basic fungi, and some strains of yeast. Terbinafine hydrochloride is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch, inhibiting ergosterol synthesis at the stage of squalene epoxidation (IC50 = 30 nM for C. albicans). Terbinafine inhibits squalene monooxygenase thereby blocking the biosynthesis of ergosterol, which is an essential component of fungal cell membranes. At 90-120 ?M, Terbinafine exhibits anti-tumor and anti-angiogenic activity by inducing cell cycle arrest at the G0/G1 stage in COLO 205 tumor cells and human vascular endothelial cells. |
| 别名 | 特比萘芬盐酸盐;盐酸特比萘酚;反-N-(6,6-二甲基-2-庚烯-4-炔基)-N-甲基-1-萘基甲胺盐酸盐;(E)-N-(6,6-二甲基-2-庚烯-4-炔基)-N-甲基-1-萘甲胺盐酸盐;(E)-N-(6,6-二甲基庚-2-烯-4-炔基)-N-甲基-1-萘甲胺盐酸盐;Terbinafine hydrochloride; trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine Hydrochloride; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride |
Terbinafine HCl信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Terbinafine HCl报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途