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Levetiracetam

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
L129699-100g 102767-28-2 询价
L129699-1g 102767-28-2 询价
L129699-250mg 102767-28-2 询价
L129699-25g 102767-28-2 询价
L129699-5g 102767-28-2 询价
产品介绍

属性

溶解性 Soluble in water (34 mg/ml at 25 °C), DMSO (34 mg/ml at 25 °C), and ethanol (34 mg/ml at 25 °C).
存贮条件 储存温度 -20°C

描述

应用 A compound which inhibits burst firing without affecting normal neuronal excitability
产品介绍 Levetiracetam is an antiepileptic which displays distinctive properties from conventional antiepileptic drugs. Displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Binds synaptic vesicle protein 2A (SV2A) and inhibits Na+-dependent Cl-/HCO3- exchange.
备注 Levetiracetam is an antiepileptic compound.
生化机理 Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.
别名 左乙拉西坦;Keppra, Keppra XR;(S)-2-(2-oxopyrrolidin-1-yl)butanamide

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途