诚信认证:
工商注册信息已核实!
快速导航
产品分类
微信二维码
Minisite
蛋白酶
MLN9708
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
M129243-100mg | 1201902-80-8 | 询价 |
M129243-50mg | 1201902-80-8 | 询价 |
M129243-1g | 1201902-80-8 | 询价 |
M129243-5mg | 1201902-80-8 | 询价 |
M129243-10mg | 1201902-80-8 | 询价 |
M129243-500mg | 1201902-80-8 | 询价 |
产品介绍
- 分子式 C20H23BCl2N2O9
- 分子量517.12
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
产品介绍 | MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM. |
备注 | MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM |
生化机理 | MLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM). |
别名 | 4-羧基-2-[(1R)-1-[[2-[(2,5-二氯苯甲酰基)氨基]乙酰基]氨基]-3-甲基丁基]-6-氧代-1,3,2-二氧硼杂环己-4-乙酸; MLN 9708; MLN-9708;Ixazomib; MLN 9708; MLN-9708;4-Carboxy-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-6-oxo-1,3,2-dioxaborinane-4-acetic acid |
MLN9708信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于MLN9708报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途