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Minisite
抗生素
Aciclovir
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
A126073-100g | 59277-89-3 | 询价 |
A126073-25g | 59277-89-3 | 询价 |
A126073-5g | 59277-89-3 | 询价 |
A126073-1g | 59277-89-3 | 询价 |
产品介绍
- 分子式 C8H11N5O3
- 分子量225.2
- Beilstein号
- EC号
- MDL号 MFCD00057880
- PubChem编号
属性
熔点 | 262°C |
溶解性 | Soluble in water (partly), DMSO (50 mg/ml), DMF (1 mg/ml), 1eq. HCl (50 mM), and dilute alkalies. |
描述
应用 | An antiviral compound that can be used to induce apoptosis. |
产品介绍 | Acyclovir 是一种合成的核苷类似物,有效作用于疱疹病毒。 |
备注 | Acyclovir is a synthetic nucleoside analogue active against herpesviruses. |
生化机理 | Acyclovir is an antiviral compound that can be used to induce apoptosis in cells transfected with herpes simplex virus thymidine kinase (HSV-TK). The compound may exert inhibitory effects through the alterations of the cell cycle in leukemia cells lines, such as p185BCR-ABL expressing OM9;22 cells, by synchronizing the G0/G1 phase. Formation of acycloguanosine triphosphate occurs through the phosphorylation of HSV-TK and can inhibit the viral DNA polymerase. Acyclovir also has the ability to inhibit the proliferation of the fibroblast cells, NIH 3T3, transformed with v-abl or bcr-abl. |
别名 | 阿昔洛韦;无环鸟苷;无环鸟嘌呤核苷;9-[(2-羟基乙氧基)甲基]鸟嘌呤;Acycloguanosine;9-[(2-Hydroxyethoxy)methyl]guanine;9-[(2-Hydroxyethoxy)methyl]guanine;2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one;2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one |
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途