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首页> 产品展示> 磷脂酶A2 来源于东部菱背响尾蛇毒液

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酶·辅酶

磷脂酶A2 来源于东部菱背响尾蛇毒液

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
P128568-1mg 9001-84-7 询价
产品介绍

属性

存贮条件 储存温度 2-8°C

描述

应用 Phospholipase A2 has been used in phospholipase assay and to determine rat renal proximal tubular segments (PTS) viability during oxygenation and hypoxia-reoxygenation.
产品介绍 Phospholipase A2 is a member of the class of heat-stable, calcium-dependent enzymes catalyzing the hydrolysis of the 2-acyl bond of 3-n-phosphoglycerides. The enzyme has a molecular weight of 30,000 daltons. Phospholipase A2 is activated by Ca2+. It is inhibited by zinc, barium, and manganese ions. Activity values for phospholipase A preparations which are derived from titrimetric assay procedures can be quite dependent on source and type of lecithin, its preparation as a substrate emulsion, other components of the reaction mixture, and the method and instrumentation used.
备注 A chromatographically purified, dialyzed, lyophilized powder.
生化机理 Hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. Aggressively attacks phospholipids in membranes of intact cells. It has a high catalytic activity on aggregated substrates compared to monomeric substrates.
别名 ;PLA2;Lecithinase A;Phosphatidylcholine 2-acylhydrolase

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途