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LC Columns

PolarAdvantage Reversed-Phase LC Column

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赛默飞 一般经销商 美国 订货

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产品介绍

Sulfonamide-Embedded Reversed-Phase Columns for Separating Polar Compounds

Acclaim®PolarAdvantage (PA) columns feature a patented bonding chemistry that incorporates a polar sulfonamide group near the surface of the silica particle. This unique chemistry provides good hydrolytic stability and allows a single column to resolve a wide variety of polar and nonpolar analytes. The Acclaim PA is compatible with 100% aqueous mobile phases and supports LC/MS analysis.

  • Low silanol activity for excellent peak shape with basic compounds

  • Novel polar-embedded column chemistry

  • Compatible with 0–100% organic solvent mobile phases

  • High selectivity for hydrophobic aromatic compounds

  • Wide range of applications

Conventional C18 phases are not compatible with highly aqueous mobile phases, due to dewetting. The Acclaim PA column by design has a mildly hydrophilic surface, which remains in contact with aqueous-only mobile phases, negating the problems of dewetting common with conventional reversed-phase columns.

Acclaim PA columns are available both in 3 and 5 μm particle sizes and 4.6, 3.0, and 2.1 mm diameters, with an average pore diameter of 120 Å. Acclaim PA is also available in 2.2µm RSLC format (see Acclaim Rapid Separation LC (RSLC) Columns section for more details). Acclaim PA may be used for LC/MS applications.

Applications

The Acclaim PA column can be used in a wide range of applications in pharmaceutical, environmental, food testing, and product-quality testing. These columns also give efficient separations with good peak shapes for compounds of life science (nucleic acid and bases) and pharmaceutical interest (sulfonamides) using highly aqueous mobile phases.


Acclaim PolarAdvantage: Rugged Polar-Embedded Reversed-Phase Columns for the Analysis of Polar and Nonpolar CompoundsSpecifications
Surface coverage2.7 μmol/m2
End-cappedYes
Metal impurity (Na, Fe, Al)<10.0 ppm Total Metal
<3.0 ppm Individual Metal
Pore volume1.0 mL/g
Average pore diameter120Å
Surface area300 m2/g
pH range2–8
Temperature<60°C
Starting materialUltrapure silica
Particle size3 and 5µ
Particle shapeSpherical
Particle size distribution (40/90)<1.3
Total carbon content17%


Fat-soluble vitamins and carotenoids in a vitamin tablet.

Loratidine and pseudo-ephedrine in a time-release tablet.

LC separation of nitrosamines, as specified in EPA 8270.

Phospholipids in egg lecithin.


Standard particle sizes are 3 and 5 μm. Available in 2.1, 3.0, and 4.6 mm i.d. Lengths are 50, 100, and 150 mm. Capillary formats are available in 75 and 300 μm, 1.0 mm, and custom diameters, and in 50, 150, or 250 mm lengths. Micro precolumn and nano precolumn cartridges are available in several formats. Guard columns in both 2.0 and 4.3 mm sizes packed with 5 μm particles are recommended. Columns for fast LC are listed in the RSLC section.

Analytical Columns
Acclaim PA, 3 µm Analytical (2.1 x 50 mm)063174
Acclaim PA, 3 µm Analytical (2.1 x 100 mm)061316
Acclaim PA, 3 µm Analytical (2.1 x 150 mm)061317
Acclaim 120, PA, 3µm Analytical (2.1 x 250mm)076215
Acclaim PA, 3µm Analytical, (3.0 x 50mm)068972
Acclaim 120, PA, 3µm Analytical (3.0 x 100mm)076214
Acclaim PA, 3 µm Analyitcal (3.0 x 150 mm)063693
Acclaim PA, 3 µm, Analytical, (3.0 x 250 mm)070079
Acclaim PA, 3 µm Analytical (4.6 x 150 mm)061318
Acclaim 120, PA, 3µm Analytical (4.6 x 100mm)076216
Acclaim PA, 5 µm Analytical (4.6 x 50 mm)061319
Acclaim PA, 5 µm Analytical (4.6 x 150 mm)061320
Acclaim PA, 5 µm Analytical (4.6 x 250 mm)061321
Guard Columns
Acclaim PA, 5µm,2mm Guard Cartridges, (2.1 x 10mm), 2 ea; requires holder 069580069691
Acclaim PA, 5µm Guard Cartridges (3 x 10mm), 2ea, requires holder 069580071983
Acclaim PA, 5 µm Guard Cartridges, (4.6 x 10 mm), 2 ea (use V-2 Holder)069698
Acclaim SST Guard Cartridge Holder V-2069580
Acclaim Guard Kit (Holder and coupler) V-2069707
Guard to Analytical Column Coupler V-2074188
Acclaim RSLC PA Analytical Columns
Acclaim RSLC PA, 3 µm Analytical (3.0 x 33 mm)066274
Acclaim PA, 3µm Analytical, (3.0 x 50mm)068972
Acclaim RSLC PA, 3 µm Analytical (3.0 x 75 mm)066275
Acclaim PA, 3 µm Analyitcal (3.0 x 150 mm)063693
Acclaim RSLC PA, 2.2µm, 2.1 x 50 mm072622
Acclaim RSLC PA, 2.2µm, 2.1 x 30 mm072621
Acclaim RSLC PA, 2.2µm, 2.1 x 100 mm072623
Acclaim RSLC PA, 2.2µm, 2.1 x 150 mm072624
Acclaim RSLC PA, 2.2µm Analytical (2.1 x 250mm)074813
Acclaim RSLC PA, 2.2µm, 3 x 30mm072625
Acclaim RSLC PA, 2.2µm, 3 x 100mm072627
Acclaim RSLC PA, 2.2µm, 3 x 50mm072626


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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途