SNS-314 Mesylate-分析测试百科网

SNS-314 Mesylate

面议

分子式 C18H15ClN6OS2.CH4O3S 分子量527.04 属性溶解性 DMSO 105 mg/mL Water 6 mg/mL Ethanol <1 mg/mL 存贮条件储存温度-20°C //decorateTabl

400-6699-117 转1000

耗材描述

溶解性	DMSO 105 mg/mL Water 6 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

备注	SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.
生化机理	SNS-314 is inhibitor of Aurora kinases A(IC50=9.0nM), B(IC50=31nM), and C(IC50=3.4nM).
别名	M1-(3-chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea Mesylate;M1-(3-chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea Mesylate