MK-0752-分析测试百科网

MK-0752

面议

分子式 C21H21ClF2O4S 分子量442.91 属性溶解性 DMSO 89 mg/mL Water <1 mg/mL Ethanol 45 mg/mL 存贮条件储存温度-20°C //decorateTable('prod

400-6699-117 转1000

耗材描述

溶解性	DMSO 89 mg/mL Water <1 mg/mL Ethanol 45 mg/mL
存贮条件	储存温度-20°C

备注	MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2.
生化机理	MK-0752 is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for Aβ40 in human SH-SY5Y cells. MK-0752 is useful in treatment of Alzheimer’s disease
别名	3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid;3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid