M126008-10mgMK-0752
面议
- 阿拉丁
- 生产商
- M126008-10mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C21H21ClF2O4S
- 分子量442.91
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
备注 | MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2. |
生化机理 |
MK-0752 is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for Aβ40 in human SH-SY5Y cells. MK-0752 is useful in treatment of Alzheimer’s disease |
别名 | 3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid;3-((1r,4s)-4-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanoic acid |
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