PD153035 HCl
面议
- 阿拉丁
- 生产商
- 国产
- 上海
- 现货
- 全国
- 3
- 0
分子式 C16H14BrN3O2·HCl 分子量396.67 MDL号 MFCD01074805 属性 溶解性 Soluble in DMSO (10 mM) with gentle warming, water ( <1 mg/mL
| 货号 | CAS号 | 操作 |
|---|---|---|
| P129384-250mg | 183322-45-4 | 询底价 |
| P129384-50mg | 183322-45-4 | 询底价 |
| P129384-10mg | 183322-45-4 | 询底价 |
耗材描述
- 分子式 C16H14BrN3O2·HCl
- 分子量396.67
- MDL号 MFCD01074805
属性
| 溶解性 | Soluble in DMSO (10 mM) with gentle warming, water ( <1 mg/mL at 25 °C), and ethanol ( <1 mg/mL at 25 °C). |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A potent inhibitor of epidermal growth factor (EGF) receptor tyrosine kinase |
| 产品介绍 | PD153035 HCl是一种有效的，特异性的EGFR抑制剂，Ki和IC50分别为5.2 pM和29 pM；对PGDFR， FGFR， CSF-1，InsR和Src几乎无作用。 |
| 备注 | PD153035 is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src. |
| 生化机理 | PD 153035 Hydrochloride is an extremely potent inhibitor of EGFR (epidermal growth factor receptor) tyrosine kinase (IC50 = 25 pM). Only inhibits other purified tyrosine kinases at micromolar or higher concentrations. |
| 别名 | 4-[(3-溴苯基)氨基]-6,7-二甲氧基喹唑啉盐酸盐盐;4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride;AG 1517;PD 153035;SU 5271;ZM 252868 |
猜你喜欢
感兴趣产品