6,7-二甲氧基香豆素
面议
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分子式 C11H10O4 分子量206.19 Beilstein号 EC号 204-369-0 MDL号 MFCD00006871 PubChem编号 24855271 属性 熔点 143-145°C 溶解性 Soluble in DMSO
| 货号 | CAS号 | 操作 |
|---|---|---|
| D101246-1g | 120-08-1 | 询底价 |
| D101246-250mg | 120-08-1 | 询底价 |
| D101246-25g | 120-08-1 | 询底价 |
| D101246-5g | 120-08-1 | 询底价 |
耗材描述
- 分子式 C11H10O4
- 分子量206.19
- Beilstein号
- EC号 204-369-0
- MDL号 MFCD00006871
- PubChem编号 24855271
属性
| 熔点 | 143-145°C |
| 溶解性 | Soluble in DMSO (15 mg/ml), and water (partly miscible). |
| 密度 | 1.2480 |
描述
| 应用 | An agent that can up-regulate the expression and activate CAR |
| 产品介绍 | Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation through activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells. |
| 别名 | 蒿属香豆素;Scoparone;6,7-Dimethylesculetin;6,7-Dimethoxy-2H-chromen-2-one;6,7-Dimethoxy-2-benzopyrone |
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