蛋白质/抗原/多肽
PolyclonalRabbitAntiPancreasDuodenumHomeobox-1（PDX-1）
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| Prospec | 暂无 | 暂无 | 现货 |
产品介绍
| Catalogue Number | ANT-162 |
| Synonyms | IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1. |
| Type | Polyclonal Rabbit Antibody. |
| Introduction | PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, it is required for maintaining the hormone-producing phenotype of the beta-cell. |
| Host | Rabbit. |
| Immunogen | Recombinant PDX1 E.Coli derived. |
| Specificity | Human and Mouse PDX-1. |
| Molecular Weight | 35-40 kDa. |
| Stability | Stable for 2 yeas at -20°C. Avoid freeze/thaw cycles. |
| Application | Western Blot: 1:1,000 Immunohistochemistry: 1:500 Optimal working dilutions must be determined by end user. Routinely evaluated by western blot on lysates of rat pancreatic cell line INS-1. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途