蛋白质/抗原/多肽
RatAntiMouseInterleukin-10(IL-10)
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
Prospec | 暂无 | 暂无 | 现货 |
产品介绍
Catalogue Number | ANT-113 | ||||||
Synonyms | B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor. | ||||||
Type | Rat Anti Mouse Monoclonal. | ||||||
Introduction | IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. | ||||||
Clone | NYRmIL-10. | ||||||
Immunogen | r.Murine IL-10. | ||||||
Ig Subclass | Rat IgM. | ||||||
Purification Method | Boric Acid precipitation. | ||||||
Protein concentration | 1mg/ml in PBS (after reconstitution). | ||||||
Shipping Conditions | Antibody is shipped lyophilized at ambient temperature. | ||||||
Storage Procedures | In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | ||||||
Reconstitution | Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4oC. | ||||||
Applications | Direct ELISA, Western Blot, Immuneprecipitation Immunohistochemistry, Intracellular staining. | ||||||
Titer | By direct ELISA, 1:5,000 dilution will yield 0.1 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). | ||||||
Usage | Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||||||
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途